2024 Summer Intern - Translational Medicine OMNI Biomarkers

Department Summary

The Translational Medicine department at Genentech informs the clinical development of novel personalized therapeutics through the establishment of biomarker strategies aimed to study the molecular pathways driving disease and to characterize the mechanism of action of our therapeutics. We focus on prognostic, predictive, and pharmacodynamic biomarkers to enable our vision of “the right drug for the right patient at the right dose”. As a member of the inflammatory bowel disease (IBD) biomarker team, this participant will gain hands-on experience in the use of in vitro organoid culture and biomarker assay development while supporting diverse clinical programs. Specifically, the participant will utilize organoid cultures and additional multiple biomarker discovery methods to identify and assess biomarker candidates in relevant disease biofluids to support development of biomarker assays to support preclinical and clinical inflammatory bowel disease programs. The participant will also have the opportunity to understand how the assessment of these analytes impacts the biomarker strategy for specific clinical programs and how biomarkers are used to support drug development.

This internship position is located in South San Francisco, On-Site

Key Responsibilities

To perform organoid culture experiments that will be used to support biomarker discovery and development efforts for multiple IBD programs.

To collaborate cross functionally with interdisciplinary teams supporting IBD molecules.

To write up-to-date standard operating procedures for organoid culture and biomarker discovery and development methods

To provide a final presentation on the major findings

Program Highlights

• Intensive 12-weeks, full time (40 hours per week) paid internship.

• Program start dates are in June 2023.

• Ownership of challenging and impactful business-critical projects.

• Work with some of the most talented people in the biotechnology industry.

• Final presentations of project work to senior leaders.

• Lead or participate in intern committees to design and coordinate program events and initiatives.

• Professional & personal development curriculum throughout the program, including networking opportunities, workshops, and panel discussions.

• Participate in volunteer projects, social events, and team-building activities.

Who You Are

Education:

• Current graduate students (Master's or PhD) who are available to work full time for the duration of the internship

Preferred majors: Cell / Molecular / Cancer Biology, Biochemistry, Immunology, Biological engineering or related disciplines

Other Qualifications

• Excellent communication, collaboration, and interpersonal skills.

• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

• Ability to work independently in a collaborative environment.

• Detail-oriented and self-directed individuals with hand-on experience in molecular biology and cell biology techniques (i.e. western blots, cytometry, imaging, immunoassays, sequencing, bioinformatics, proteomics, or cell culture)

• Experience with intestinal organoid culture methods and/or inflammatory disease models is preferred, but not required.

Along with the submission of your CV, a cover letter is optional.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location for this position of California is $22.00 - $55.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.