Roche

Intern - Machine learning for antibody design (m/f/d)


PayCompetitive
LocationPenzberg/Bavaria
Employment typePart-Time

This job is now closed

  • Job Description

      Req#: 202305-111670

      The Position

      Your Team

      We are seeking an intern either pursuing, or recently graduated from a MSc/PhD degree with expertise in advanced data analytics and machine learning to help us explore its potential applications in therapeutic antibody design. You will join the “birthplace” of therapeutic proteins in Roche’s discovery unit and work on an innovative project applying advanced analytics and machine learning approaches to protein engineering.

      Your Tasks

      The key objectives of this project are three-fold: 1) To study the immune repertoire dynamics after immunization; 2) To apply machine learning to derive sequence characteristics within the repertoire; and 3) To add to the in-house capability in using advanced statistical and machine learning models for harnessing future sequencing datasets.

      The anticipated impact of the project is an accelerated process for antibody discovery and optimization. You are expected to disseminate the findings to our cross-functional project teams.

      We are looking for individuals who are:

      • Creative problem solvers, quick learners and comfortable experimenting with new approaches

      • Demonstrate high productivity and enjoy dealing with ambiguity and applying novel methodologies

      Responsibilities:

      • Collaborate with the host team and other stakeholders to evaluate potential machine learning techniques and applications

      • Design, build and interpret machine learning algorithms to address selected research questions (including preparing the input data)

      • Proactively share learnings and knowledge to support the development of the wider Roche Advanced Analytics community

      • Help shape the direction of machine learning and artificial intelligence within Roche

      Preferred Experience and Competencies :

      • Basic knowledge of software development and fluency in at least one statistical programming language (Python, R, etc.)

      • Understanding of machine learning framework (e.g. sklearn, PyTorch)

      • Experience with single cell data analysis or large language models. Appreciated: Preferred experience in protein sequence and structure modellingKnow

      • Experience with technologies required to undertake analyses on large data sources or with computationally intensive steps (Parallelization, HPC cluster computing, Container)

      • Strong communication and collaboration skills

      • Experience implementing reproducible research practices like version control (e.g. using Git) is a plus.

      Qualifications Required:

      • BSc/MSc degree candidate or recent graduate in Bioinformatics, Statistics, Biomedical Engineering, Computer Science; or Biology background with experience in single cell sequencing

      Your benefits

      • Flexible time management

      • 1958€ salary per month for a full-time internship > 3 months

      • Reduced meal prices (-50 %) in our employee canteen

      • Networking with other students

      • The possibility of accommodation in the Roche Boarding House or convenient transport connections to Munich with the Roche Shuttle

      Your application

      Simply upload your resume.

      We are looking forward to your application for a period of 6 months !

      #ai, #ml, #machinelearning, #statistics

      #analytics, #joinRoche, #haveAnImpact, #dataScience

      Your contact to us! With people. For people.

      Do you need more support?

      Our Talent Acquisition Team welcomes your questions. Please send an email to

      germany.talent_acquisition@roche.com

      Who we are

      At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

      Roche at Penzberg, near Munich, employs more than 7,000 people. The site is one of the largest biotechnology centers in Europe and the only Roche site with research, development and production for both Pharmaceuticals and Diagnostics under one roof. From your beginning with Roche, our motivated team will welcome and support you. Numerous opportunities for personal development, flexible work hours, attractive compensation packages and special family assistance programs are available.

      Roche is an Equal Opportunity Employer.

  • About the company

      606018 F. Hoffmann-La Roche AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics.