Strategic team efforts. Seamless synergy. Tangible results.

ScientistX2 Bioscience team under the leadership of Stuart Farrow

£33,000 - £38,150 (dependent on experience) plus benefits

Reports to: Senior Scientist

Directorate: Research & Innovation

Contract: Permanent

Hours: Full time 35 hours per week (we can consider 4 days weeks, 28 hours)

Location: Granta Park, Cambridge or The Francis Crick Institute, London

Closing date: 21 Aug 2024 23:55

Please let us know if there is anything about the recruitment process that you would like to discuss, or if there are any changes or adjustments that would make it easier for you to apply. Please contact recruitment@cancer.org.uk or 020 3469 8400 as soon as possible.

Recruitment process: Initial virtual screening followed by in person interview with presentation.

Interview date: 5/6 September for in person interview

Please note: Cancer Research UK is able to consider visa sponsorship for this vacancy. If this applies to you, please ensure that this is clearly marked on your application.

At Cancer Research UK, we exist to beat cancer.

Do you want to help deliver breakthrough medicines for cancer patients?

We are looking for a proactive and ambitious scientist to join CRUKs Bioscience team at Cancer Research Horizons.

As a scientist within the Bioscience team you will work to design, perform and interpret drug discovery studies using tool compounds/antibodies, gene knockdown and/or gene editing approaches. You will also conduct and interpret phenotypic assays in cell line models and work on assay development.

You don’t necessarily need oncology experience for this role if you can demonstrate experience in cell culture and come with a proactive mindset and desire to learn. This is a real opportunity to learn new skills and techniques and grow independence in a supportive team environment, where we can offer mentorship, a chance to meet with academic partners, work across a variety of assays, and attend conferences that celebrate our science. You’ll also be surrounded by people as dedicated to beating cancer as you.

About CRUK Drug Discovery

As the world’s biggest medical research charity, we have helped bring eleven new cancer drugs to market. However, there is still an urgent need to bring more effective treatments to patients faster.

Cancer Research Horizons (CRH) was established in 2022, bringing together Cancer Research UK’s established drug discovery teams under one organisation and leadership team, combining our unique pipeline of world class biology, cutting edge technology platforms and clinical expertise. We aim to tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.

What will I be doing?

In this lab-based role you will:

• Work to progress key experimental objectives within project teams, taking responsibility for the timely delivery of objectives

• Carry out work such as:

  • Designing, performing, and interpreting drug discovery studies using tool compounds/antibodies, gene knockdown and/or gene editing approaches

  • Conducting and interpreting phenotypic assays in cell line models

  • Assay development

• Work collaboratively within the Bioscience team and interact positively with multi-disciplinary research teams and external collaborators

• Critically interpret data and summarise effectively for different audiences

• Maintain accurate and up to date electronic laboratory notebook

What are you looking for?

• PhD in Biological Science (or equivalent experience)

• Mammalian cell culture

• Target validation techniques (siRNA, shRNA, CRISPR, overexpression, tool compounds/antibodies)

• Proactive attitude

• Ability to work in a team and collaborate effectively

• Flexible mindset, with the ability to adapt to new challenges and a fast-paced setting

• Strong organisational skills

Our organisation values are designed to guide all that we do.

Bold: Act with ambition, courage and determination

Credible: Act with rigour and professionalism

Human : Act to have a positive impact on people

Together: Act inclusively and collaboratively

We’re looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.

If you’re interested in applying and excited about working with us but are unsure if you have the right skills and experience we’d still love to hear from you.

What will I gain?

We create a working environment that supports your wellbeing and provide a generous benefits package, a wide range of career and personal development opportunities and high-quality tools. Our policies and processes enable you to improve your work-life balance, take positive steps in your career and achieve your personal wellbeing goals. You will be working in a dynamic drug discovery organisation with the opportunity to collaborate with colleagues in medicinal chemistry, protein sciences, CRISPR screening, structural biology, DMPK, antibody generation and bioscience teams.

You can explore our benefits by visiting our careers web page.

How do I apply?

We operate an anonymised shortlisting process in our commitment to equality, diversity and inclusion. CVs are required for all applications; but we won’t view them until we invite you for an interview. Instead, we ask you to complete the work history section of the online application form and answer the screening questions for us to be able to assess your skills fairly and objectively.

For more information on this career opportunity please visit our website or contact us at recruitment@cancer.org.uk .

For more updates on our work and careers, follow us on: Linked In, Facebook, Instagram, X and YouTube.

Our vision is to create a charity where everyone feels like they belong, benefits from and participates in, the work we do. We actively encourage applications from people of all backgrounds and cultures, in particular those from ethnic minority backgrounds who are currently under-represented.

We want to see every candidate performing at their best throughout the job application process, interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact recruitment@cancer.org.uk or 0 20 3469 8400 as soon as possible.

Unfortunately, we are unable to recruit anyone below the age of 18, so that we can protect young people from health & safety and safeguarding risks.